Improved selection of participants in genetic longevity studies: family scores revisited
نویسندگان
چکیده
منابع مشابه
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The amount of research on human aging and longevity has been growing rapidly in recent years. Multidisciplinary approaches, which integrate classic population genetics methods with the principles of epidemiological and demographic investigation, are emerging as powerful tools for disentangling the complex gene network which modulates human lifespan. We try to summarize the different approaches ...
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متن کاملA family longevity selection score: ranking sibships by their longevity, size, and availability for study.
Family studies of exceptional longevity can potentially identify genetic and other factors contributing to long life and healthy aging. Although such studies seek families that are exceptionally long lived, they also need living members who can provide DNA and phenotype information. On the basis of these considerations, the authors developed a metric to rank families for selection into a family...
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ژورنال
عنوان ژورنال: BMC Medical Research Methodology
سال: 2021
ISSN: 1471-2288
DOI: 10.1186/s12874-020-01193-7